Abbreviation: LXR α

Liver X receptors are classified into subfamily thyroid hormone receptor-like and are important regulators of cholesterol, fatty acid and glucose homeostasis. There are two different isoforms of the liver x receptor (α and β). For more information see Wikipedia.

Performance

This is an overview of the performance of our protocols on different forms of liver x receptor alpha

Active

Tresholds
Score Sensitivity Specificity PPV NPV
-11.90.2660.9820.698.5
-10.70.5170.846.198.9
-9.80.7560.63.699.2

More negative score means greater possibility for binding.

Sensitivity represents fraction of true positives.

Specificity represents fraction of true negatives.

Files: 3IPS, conf_LXRalpha, ,