Abbreviation: LXR α
Liver X receptors are classified into subfamily thyroid hormone receptor-like and are important regulators of cholesterol, fatty acid and glucose homeostasis. There are two different isoforms of the liver x receptor (α and β). For more information see Wikipedia.
This is an overview of the performance of our protocols on different forms of liver x receptor alpha
| Score | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| -11.9 | 0.266 | 0.98 | 20.6 | 98.5 |
| -10.7 | 0.517 | 0.84 | 6.1 | 98.9 |
| -9.8 | 0.756 | 0.6 | 3.6 | 99.2 |
More negative score means greater possibility for binding.
Sensitivity represents fraction of true positives.
Specificity represents fraction of true negatives.
Files: 3IPS, conf_LXRalpha, ,