Abbreviation: GR

Glucocorticoid receptor is nuclear receptor belonging to 3-ketosteroid receptors. It regulates development, metabolism and immune response. For details see Wikipedia and Proteopedia.

Performance

This is an overview of the performance of our protocols on different forms of glucocorticoid receptor

Agonist

Tresholds
Score Sensitivity Specificity PPV NPV
-10.70.2560.9820.098.5
-9.70.5060.8596.798.9
-7.30.7530.1591.897.0

More negative score means greater possibility for binding.

Sensitivity represents fraction of true positives.

Specificity represents fraction of true negatives.

Antagonist

Tresholds

More negative score means greater possibility for binding.

Score Sensitivity Specificity PPV NPV
-9.80.2640.833.098.3
-9.20.5160.6492.998.5
-8.50.7830.3932.598.9

More negative score means greater possibility for binding.

Sensitivity represents fraction of true positives.

Specificity represents fraction of true negatives.

Files: 3BQD, conf_GR, 3N52, conf_GR_anta