Abbreviation: ER β
Estrogen receptors are included in estrogen receptor-like subfamily with estrogen related and 3-ketosteroid receptors.There are two different forms of the estrogen receptor (α and β), each encoded by a separate gene.The ERβ is found in kidney, brain, bone, heart, lungs, intestinal mucosa, prostate, and endothelial cells. For more see Wikipedia and Proteopedia.
This is an overview of the performance of our protocols on different forms of estrogen receptor beta
| Score | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| -9.2 | 0.293 | 0.973 | 17.8 | 98.6 |
| -8.7 | 0.563 | 0.914 | 11.6 | 99.1 |
| -8.0 | 0.788 | 0.73 | 5.5 | 99.4 |
More negative score means greater possibility for binding.
Sensitivity represents fraction of true positives.
Specificity represents fraction of true negatives.
More negative score means greater possibility for binding.
| Score | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| -9.0 | 0.31 | 0.743 | 2.4 | 98.2 |
| -8.6 | 0.552 | 0.588 | 2.6 | 98.5 |
| -8.3 | 0.793 | 0.467 | 2.9 | 99.1 |
More negative score means greater possibility for binding.
Sensitivity represents fraction of true positives.
Specificity represents fraction of true negatives.
Files: 3OLS, conf_ERbeta, 1QKN, conf_ERbeta_anta