Abbreviation: ER α
Estrogen receptors are included in estrogen receptor-like subfamily with estrogen related and 3-ketosteroid receptors.There are two different forms of the estrogen receptor (α and β), each encoded by a separate gene.The ERα is found in endometrium, breast cancer cells, ovarian stroma cells, and the hypothalamus. For more see Wikipedia and Proteopedia.
This is an overview of the performance of our protocols on different forms of estrogen receptor alpha
| Score | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| -9.3 | 0.275 | 0.951 | 10.2 | 98.5 |
| -8.8 | 0.537 | 0.861 | 7.2 | 98.9 |
| -8.2 | 0.766 | 0.665 | 4.4 | 99.3 |
More negative score means greater possibility for binding.
Sensitivity represents fraction of true positives.
Specificity represents fraction of true negatives.
More negative score means greater possibility for binding.
| Score | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| -10.7 | 0.27 | 0.982 | 23.2 | 98.5 |
| -9.5 | 0.516 | 0.837 | 5.9 | 98.9 |
| -8.6 | 0.787 | 0.563 | 3.5 | 99.2 |
More negative score means greater possibility for binding.
Sensitivity represents fraction of true positives.
Specificity represents fraction of true negatives.
Files: 1A52, conf_ERalpha, 1SJ0, conf_ERalpha_anta