Abbreviation: AR

Androgen receptor is primary receptor for testosterone and dihydrotestosterone. Its main function is development and maintenance of the male sexual phenotype. For details see Wikipedia and Proteopedia.

Performance

This is an overview of the performance of our protocols on different forms of androgen receptor

Agonist

Tresholds
Score Sensitivity Specificity PPV NPV
-8.60.2690.9715.298.5
-8.10.5030.91710.898.9
-7.40.7550.7626.099.4

More negative score means greater possibility for binding.

Sensitivity represents fraction of true positives.

Specificity represents fraction of true negatives.

Antagonist

Tresholds

More negative score means greater possibility for binding.

Score Sensitivity Specificity PPV NPV
-8.40.2810.9085.898.4
-7.60.5050.723.598.6
-3.10.7520.2151.997.7

More negative score means greater possibility for binding.

Sensitivity represents fraction of true positives.

Specificity represents fraction of true negatives.

Files: 3L3X, conf_AR, 2Z4J, conf_AR_anta